ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Causes and Outcome of Systemic Inflammatory Response Syndrome in Dogs: An Observational Study of 172 Cases.
Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveTo evaluate the clinical characteristics, underlying diseases, organ dysfunctions, and survival of dogs with systemic inflammatory response syndrome (SIRS) or sepsis.
designProspective observational study from January to December, 2023.
settingSingle-center, veterinary university teaching hospital. ANIMALS: One hundred sixty-six dogs; six dogs with distinct cases of SIRS were included twice (172 cases).
interventionsNone. MEASUREMENTS AND MAIN
resultsDogs were included if they met two or more of the four SIRS criteria (hypothermia or fever; tachycardia; tachypnea; leukocytosis, leukopenia, or left shift) and had a disease causing systemic inflammation. Cases were categorized into groups (G) "nonseptic SIRS" (G1: n = 73), "sepsis" (G2: n = 92), "sepsis without organ dysfunction" (G2a: n = 25), "severe sepsis" (G2b: n = 59; dysfunction of one or more organ systems), "septic shock" (G2c: n = 8; hypotension despite adequate fluid resuscitation), and "SIRS of unclear origin" (G3: n = 7). The most common causes of SIRS/sepsis were gastrointestinal diseases (n = 61 [35.5%]), vector-borne diseases (n = 28 [16.3%]), and neoplasia (n = 22 [12.8%]). There was dysfunction of one or more organs in 114 cases (66.3%). The coagulation system was most frequently affected (n = 78 [45.3%]), followed by the cardiovascular system (n = 47 [27.3%]), respiratory tract (n = 14 [8.1%]), kidney (n = 13 [7.6%]), and liver (n = 6 [3.5%]). Overall, 128 of 165 cases (77.6%) survived until discharge (short-term), and 116 of 159 (73%) survived ≥4 weeks after discharge (long-term). Differences in outcome were found between G1 and G2 (short-term: p = 0.046, long-term: p = 0.015), with dogs in G2 having better survival. Short-term mortality was higher in cases with one or more organ dysfunctions than in cases without (p = 0.031).
conclusionsSIRS can be triggered by a variety of diseases in dogs. Strict and regular monitoring is important for early detection of organ dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.