ArticleTurkish journal of emergency medicine
Predictors of invasive mechanical ventilation requirement and mortality in hypercapnic respiratory failure: A retrospective analysis.
Article in Turkish journal of emergency medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionWhile hypercapnic respiratory failure (HRF) has been widely studied in emergency department (ED) populations, the prognostic significance of metabolic compensation and lactate levels remains unclear. This study aimed to evaluate the association of creatinine, bicarbonate (HCO
methodsThis single-center, cross-sectional study included adult patients who presented to the ED with respiratory distress and arterial partial pressure of carbon dioxide >50 mmHg between 2020 and 2023. The relationships between initial laboratory parameters and clinical outcomes were analyzed.
resultsA total of 420 patients were included (median age: 77 years [interquartile range: 68-85]; 51.4% female). The mortality rate among bedridden patients was 55.9% and 34.3% among patients diagnosed with pneumonia. Creatinine ≥1.6 mg/dL was associated with inhospital mortality (odds ratio [OR]: 3.7; 95% confidence interval [CI]: 2.044-6.696) and IMV requirement (OR: 2.323; 95% CI: 1.216-4.439). Lactate >1.5 mmol/L was also associated with higher mortality (OR: 10.441; 95% CI: 5.739-18.996). Delta HCO
conclusionsIn patients with HRF, ΔHCO
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