ArticleJournal of thoracic disease2026
Impact of core temperature management and postoperative continuous renal replacement therapy in extensive aortic arch repair for type A dissection.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Continuous renal replacement therapy (CRRT) represents a critical complication following extensive aortic arch repair for type A aortic dissection (TAAD), significantly influencing patient outcomes. This study evaluates the impact of different hypothermic circulatory arrest (HCA) temperature strategies on postoperative CRRT requirements. Methods: A total of 1,283 TAAD patients who underwent total arch replacement (TAR) with frozen elephant trunk (FET) procedure were retrospectively enrolled [2010-2018]. Patients were divided into CRRT (N=123) and non-CRRT (N=1,160) groups. Core temperature during HCA was categorized into deep hypothermia (DH) (≤20 ℃), low-moderate hypothermia (LMH) (20.1-24 ℃), high-moderate hypothermia (HMH) (24.1-28 ℃), and mild hypothermia (MH) (>28 ℃). Results: The CRRT group exhibited significantly higher early mortality (38.2% Conclusions: Higher core temperatures are associated with reduced CRRT risk during TAR with FET procedure. However, this association appears to be modified by CPB duration, and caution is warranted regarding potential renal injury associated with increased core temperatures in complex surgeries with prolonged CPB time.
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