Evidence map›Paper›PMID 42583271›Full record

ArticleIJTLD open2026

Impact of undernutrition and diabetes on the pharmacokinetics of first-line anti-TB drugs.

K Ezhumalai, P S Rao, S P Babu, S M Jeyakumar, R C Bollinger, S K Heysell, J A Tornheim, P B Narasimhan, B Thangakunam, M Paradkar and 14 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in IJTLD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

K EzhumalaiDepartment of Preventive & Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
P S RaoDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.
S P BabuDepartment of Preventive & Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
S M JeyakumarIndian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India.
R C BollingerDivision of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.
S K HeysellDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.
J A TornheimDivision of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.
P B NarasimhanDepartment of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
B ThangakunamChristian Medical College, Vellore, Ranipet campus, Tamil Nadu, India.
M ParadkarCenter for Infectious Diseases in India, Johns Hopkins India, Pune, India.
D J ChristopherChristian Medical College, Vellore, Ranipet campus, Tamil Nadu, India.
S GaikwadBJ Government Medical College and Sassoon General Hospitals, Pune, India.
V ViswanathanProf. M. Viswanathan Diabetes Research Centre, Chennai, Tamil Nadu, India.
H KornfeldDepartment of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
J J EllnerDepartment of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
P SalgameDepartment of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
C R HorsburghBoston Medical Center, Section of Infectious Diseases, Boston, MA, USA.
A N GupteDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.
A GuptaDivision of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.
V MaveCenter for Infectious Diseases in India, Johns Hopkins India, Pune, India.
S SarkarDepartment of Preventive & Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
B Perumal KIndian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India.
P SinhaBoston Medical Center, Section of Infectious Diseases, Boston, MA, USA.
RePORT India Consortium

Funding

Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and AdultsR01AI137080 · NIAID · UNIVERSITY OF VIRGINIA · PI Scott K Heysell, Leonid Kagan · 2018 to 2026
$6.3M
Developing research leaders at the intersection of malnutrition and tuberculosis in TanzaniaD43TW012247 · FIC · UNIVERSITY OF VIRGINIA · PI Scott K Heysell, STELLAH GEORGE MPAGAMA · 2022 to 2026
$1.4M
Nutritional Interventions to End Tuberculosis among Persons with HIV (NUTRIENT)K01AI167733 · NIAID · BOSTON MEDICAL CENTER · PI Pranay Sinha · 2023 to 2026
$512k
A global Infectious diseases framework to grow interdisciplinary researchK24AI187675 · NIAID · UNIVERSITY OF VIRGINIA · PI Scott K Heysell · 2025 to 2026
$292k
FIC NIH HHS D43 TW012247NIAID NIH HHS K01 AI167733NIAID NIH HHS K24 AI187675NIAID NIH HHS R01 AI137080
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

body mass indexdiabetes mellitusglycaemic statusIndiatuberculosis

Identifiers

PMID42583271
PMCPMC13460429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.