Evidence map›Paper›PMID 42583198›Full record

Trial reportOrthopedic research and reviews2026

Effect Of Intraarticular Triamcinolone Hexacetonide versus Betamethasone on Intraocular Pressure: A Prospective Randomized Study.

Hilal Yağar, Kadir Eren Biçer, Gamze Yıldırım Biçer

Registry-linked trialAbstract readCase ReportsClinical Trial
In one paragraph

Trial report in Orthopedic research and reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07242846 (EFFECT OF INTRAARTICULAR TRIAMCINOLONE HEXACETONIDE AND BETAMETHASONE ON INTRAOCULAR PRESSURE), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07242846 phase4completednot on this map

Effect of intraarticular triamcinolone hexacetonide and betamethasone on intraocular pressure: a prospective randomized study

TypeinterventionalSponsorNigde Omer Halisdemir UniversityRan2025 to 2025Enrolled80ConditionsKnee Osteoarthritis (Knee OA), Intraocular PressureArmsDiprospan, artropan
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hilal YağarDepartment of Orthopedics and Traumatology, Niğde Ömer Halisdemir University, Faculty of Medicine, Niğde, Türkiye.ORCID 0000-0001-5544-0458
Kadir Eren BiçerDepartment of Orthopedics and Traumatology, Niğde Ömer Halisdemir University, Faculty of Medicine, Niğde, Türkiye.ORCID 0000-0001-8179-9181
Gamze Yıldırım BiçerDepartment of Ophthalmology, Niğde Ömer Halisdemir University, Faculty of Medicine, Niğde, Türkiye.ORCID 0000-0003-3058-6308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Corticosteroids may cause glaucoma by increasing intraocular pressure (IOP) due to their systemic side effects. Few studies have investigated the effect of intraarticular corticosteroids (IACS) on IOP. This study aimed to evaluate the effects of IACS preparations (betamethasone and triamcinolone hexacetonide) on IOP. Methods: In this single-center randomized study, patients receiving IACS were randomized into two groups: Group 1 received betamethasone (Diprospan Results: A total of 80 patients and 160 eyes were included in the study, with 40 patients in each group. No significant change was found in ΔIOP in Group 1 (p > 0.05). A statistically significant increase in ΔIOP was observed in both eyes and in the left eye in Group 2; (both eyes: p = 0.002; left eye: p = 0.012; right eye: Conclusion: Triamcinolone hexacetonide may increase IOP after IACS more than betamethasone; caution is warranted in patients with risk factors for glaucoma. Trial Registration: The trial was registered at ClinicalTrials.gov retrospectively (No: NCT07242846, Date: 17.11.2025).

Indexed as

adverse reactionsbetamethasonedrug-related side effectsinjectionsintra-articularintraocular pressuretriamcinolone

Identifiers

PMID42583198
PMCPMC13459991

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.