ArticleJournal of thoracic disease2026
Renal artery involvement as a predictor of severe malperfusion in acute type A aortic dissection: a retrospective cohort study.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Reliable radiographic indicators to assess the severity and prognosis of acute type A aortic dissection (ATAAD) are lacking. This study investigates whether renal artery involvement (RAI) on preoperative imaging serves as a marker of extensive branch vessel compromise and malperfusion. Methods: This retrospective study analyzed 471 consecutive patients who underwent open surgical repair for ATAAD between January 2020 and June 2022. RAI was defined on computed tomography angiography (CTA) as dissection membrane extension to the renal artery ostium. Patients were divided into RAI (n=289) and non-RAI (n=182) groups. Propensity score matching (PSM) minimized baseline differences. Multivariable ordered logistic regression assessed the association between RAI and the number of malperfused organ systems. Cox regression identified risk factors for mortality. Results: The RAI group exhibited more extensive aortic branch involvement (P<0.05), required more concomitant branch procedures, and had a higher incidence of end-organ malperfusion (P=0.006) and serious adverse events (SAEs) (P=0.009), consistent after PSM. Ordered logistic regression showed that RAI was associated with malperfusion [odds ratio (OR) =2.00, 95% confidence interval (CI): 1.25-3.27, P=0.005]. Cox regression identified RAI as an independent risk factor for overall mortality [hazard ratio (HR) =3.48, 95% CI: 1.15-10.47, P=0.03] and mid-term mortality (HR =3.42, 95% CI: 1.14-10.31, P=0.03). Long-term follow-up recorded 11 deaths among hospital survivors; no significant association was observed between RAI and permanent dialysis dependence (log-rank P=0.18). Conclusions: RAI on preoperative CTA is a simple, objective indicator of extensive aortic branch compromise and higher malperfusion burden in ATAAD, identifying a high-risk cohort with worse perioperative outcomes and reduced mid-term survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.