Sleep Disturbance in Adults with Type 2 Diabetes: Psychosocial Factors Across Anxiety Symptom Groups.

Purpose: Sleep disturbance is common in adults with type 2 diabetes mellitus (T2DM), but associated psychosocial factors may vary by anxiety symptom status. We examined the prevalence of sleep disturbance and associated factors among adults with T2DM in Hainan Province, China. Patients and Methods: This multicenter cross-sectional study included 1200 adults with clinician-confirmed T2DM recruited from endocrinology departments of eight tertiary hospitals. Anxiety symptoms were defined as Generalized Anxiety Disorder-7 score ≥5, and sleep disturbance as Athens Insomnia Scale score ≥6. Multivariable logistic regression models were fitted separately for participants with and without anxiety symptoms. Secondary and sensitivity analyses examined continuous sleep scores, a higher anxiety threshold, and overlap from sleep-related questionnaire items. Results: Of 1200 participants, 309 had anxiety symptoms and 891 did not. Sleep disturbance affected 631 participants (52.6%) and was more prevalent among those with anxiety symptoms than among those without (82.2% vs 42.3%). In the anxiety-symptom subgroup, higher Patient Health Questionnaire-9, Beck Hopelessness Scale, and post-traumatic stress symptom scores were associated with greater odds of sleep disturbance. In the subgroup without anxiety symptoms, higher Patient Health Questionnaire-9 and Perceived Deficits Questionnaire scores and higher educational level were associated with sleep disturbance. Conclusion: Sleep disturbance was common, particularly among participants with anxiety symptoms. Anxiety-stratified analyses identified different exploratory patterns of associated factors. These cross-sectional findings may support more focused sleep and psychosocial assessment but do not establish causal relationships, validated clinical subtypes, or treatment recommendations.