ArticleInternational journal of clinical pediatric dentistry2026
Enhanced Analgesic Outcomes with Low-dose Dexmedetomidine and Lignocaine-Adrenaline in Pediatric Inferior Alveolar Nerve Block: A Randomized Trial.
Article in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim and background: The present double-blind randomized trial was conducted to evaluate if dexmedetomidine enhances the effect of lignocaine-induced local anesthesia in 4-8-year-old children undergoing mandibular molar pulpectomies. Materials and methods: This double-blind randomized controlled trial included 60 pediatric patients scheduled for mandibular molar pulpectomy, who were allocated into 2 groups. In group A ( Results: Children administered the dexmedetomidine-lignocaine combination demonstrated lower pain scores than those who received lignocaine alone, as shown by the Wong-Baker scale ( Conclusion: The low-dose dexmedetomidine successfully enhanced the effect of lignocaine by providing faster and enhanced anesthesia for better pain control. Clinical significance: Incorporating low-dose dexmedetomidine with lignocaine in pediatric pulpectomies enhances local anesthetic efficacy by reducing pain, shortening onset, and prolonging duration of anesthesia. This combination offers a safer and more comfortable treatment experience for young children.
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