Evidence map›Paper›PMID 42582619›Full record

ReviewHealth science reports2026

Efficacy and Safety of Chinese Herbal Medicine for Patients With Chronic Wound: A Systematic Review and Meta-Analysis.

Xia Hao, Dongzhen Zhu, Jinbo Zhang, Tingting Liu, Zhimin Yao, Qingju Sun, Bin Yao, Wei Yang

Abstract readReview
In one paragraph

Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xia HaoTianjin rehabilitation and convalescent center Tianjin PR China.
Dongzhen ZhuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Department PLA General Hospital Beijing PR China.
Jinbo ZhangTianjin rehabilitation and convalescent center Tianjin PR China.
Tingting LiuDepartment of Laboratory Diagnosis The 971th Hospital Qingdao PR China.
Zhimin YaoAcademy of Medical Engineering and Translational Medicine Tianjin University Tianjin PR China.
Qingju SunDepartment of Laboratory Diagnosis The 971th Hospital Qingdao PR China.
Bin YaoAcademy of Medical Engineering and Translational Medicine Tianjin University Tianjin PR China.ORCID https://orcid.org/0000-0002-0709-8683
Wei YangTianjin rehabilitation and convalescent center Tianjin PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Chronic wounds, characterized by complex pathogenesis, prolonged healing duration, and high disability rates, pose significant therapeutic challenges. While accumulating evidence suggests that Traditional Chinese Medicine (TCM) exhibits unique advantages in managing this condition, a comprehensive systematic evaluation of its efficacy and safety remains lacking. This study aims to critically assess the therapeutic effects and adverse event profiles of TCM interventions for chronic wounds. Methods: A systematic review and meta-analysis of international online databases was conducted following PRISMA guidelines. PubMed, Embase, the Cochrane Library, OVID-Medline, and the China National Knowledge Infrastructure (CNKI) database were searched using appropriate keywords from January 2013 to June 2024. RevMan 5.4 software recommended by the Cochrane Collaboration was used for meta-analysis, was analyzed and the heterogeneity of statistical results using statamp-64. Results: The analysis incorporated 128 observational studies involving 9833 participants. TCM interventions demonstrated superior outcomes compared to controls across multiple endpoints: (1) Significant reduction in TCM syndrome scores (SMD = -0.84, 95% CI: -1.05 to -0.63; Conclusion: Our meta-analysis demonstrates that TCM-based therapies not only effectively alleviate clinical symptoms and improve quality of life but also accelerate wound repair in chronic wound patients without severe adverse reactions.

Indexed as

chronic woundMeta‐analysisTraditional Chinese Medicine

Identifiers

PMID42582619
PMCPMC13458026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.