ArticleQuantitative imaging in medicine and surgery2026
ASL, DTI, and T1 mapping in identifying immune and non-immune pathogenic factors of chronic allograft injury.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Chronic allograft injury (CAI) has a complex etiology and various clinical and pathological manifestations, posing challenges for clinical diagnosis and treatment. This study aimed to explore the value of arterial spin labeling (ASL), diffusion tensor imaging (DTI), and T1 mapping in identifying the causes of CAI. Methods: This study included 69 kidney transplant recipients. Based on the estimated glomerular filtration rate (eGFR) and biopsy results, the recipients were classified into three groups: Group A, recipients with good renal allograft function (eGFR ≥60 mL/min/1.73 m Results: Renal blood flow (RBF) was higher in the recipients with normal renal allograft function than in those with CAI. Cortical and medullary apparent diffusion coefficient (ADC) values were lower in the immune factors group (2.05±0.22/2.06±0.22 ×10 Conclusions: ASL, DTI, and T1 mapping can distinguish between recipients with normal renal allograft function and those with CAI. Further, DTI and T1 mapping can differentiate between immune and non-immune pathogenic factors of CAI.
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