Evidence map›Paper›PMID 42582509›Full record

ArticleInternational journal of clinical pediatric dentistry2026

Anesthetic Efficacy of Lignocaine Added with Magnesium Sulfate during Pulpectomy in Children with Irreversible Pulpitis: A Prospective, Split-mouth, Randomized Controlled Trial.

Chilukuri Raghuram, Deepika Pai, Kalyana C Pentapati, Nekkanti Sridhar

Abstract read
In one paragraph

Article in International journal of clinical pediatric dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Chilukuri RaghuramDepartment of Pediatric and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Deepika PaiDepartment of Pediatric and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Kalyana C PentapatiDepartment of Public Health Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0002-5462-5677
Nekkanti SridharDepartment of Pediatric and Preventive Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0001-6219-6641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim and background: Pain control is one of the major challenges of pediatric dentistry. Pain control after an inferior alveolar nerve block (IANB) during pulpectomy is often challenging in pediatric patients. Hence, this study aims to investigate the effect of addition of magnesium sulfate (MgSO Methods: 32 patients fulfilling the inclusion criteria were selected in this split-mouth study design. Patients received either test or control solutions at two different appointments as an inferior alveolar nerve block. The test solution contains MgSO Results: Pain scores recorded in the test side were significantly lower compared to those recorded in the control side during access opening (FLACC scores on the test side and control side were 2.00 ± 0.76 and 2.47 ± 0.62; HP-VAS scores in the test and control side were 25.72 ± 5.75 and 28.44 ± 5.64). Pain scores during pulp extirpation are: HP-VAS on the test side is 36.68 ± 1.07, and on the control side is 55.74 ± 1.69; FLACC scores on the test and control sides are 2.05 ± 0.94 and 2.61 ± 0.57, respectively. Conclusion: Magnesium sulfate, when added to lignocaine local anesthesia (LA), was successful in enhancing the depth of pulpal anesthesia. Clinical significance: Addition of magnesium sulfate enhances the depth of local anesthesia while treating primary teeth with chronic irreversible pulpitis.

Indexed as

Inferior alveolar nerve blockLignocaine hydrochlorideMagnesium sulfatePulpal anesthesiaPulpectomy

Identifiers

PMID42582509
PMCPMC13457756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.