Evidence map›Paper›PMID 42582357›Full record

ArticleFrontiers in neuroscience2026

Seeing clearly with CLARI-O: a window into cellular architecture, interactions, and morphology of organoid models.

Samra Beyene, Martin Thunemann, Natalie Baker Campbell, Elizabeth K Kharitonova, Shira Klorfeld-Auslender, Farzad Mortazavi, Ella Zeldich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Samra BeyeneDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.
Martin ThunemannDepartment of Biomedical Engineering, Boston University, Boston, MA, United States.
Natalie Baker CampbellDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.
Elizabeth K KharitonovaDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.
Shira Klorfeld-AuslenderPicower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, United States.
Farzad MortazaviDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.
Ella ZeldichDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.

Funding

Understanding neuronal dysfunction in Down Syndrome using assembloids and xenotransplanted cortical organoidsRF1AG088529 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI THUNEMANN, MARTIN, ZELDICH, ELLA · 2024 to 2024
$2.4M
The contribution of X-chromosome-linked genes to cellular phenotypes and AD-related pathology in Down SyndromeR21AG080269 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZELDICH, ELLA · 2023 to 2024
$454k
Epigenetic Determinants in Oligodendrocyte Maturation in Down SyndromeR21NS125469 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MEDALLA, MARIA, ZELDICH, ELLA · 2022 to 2022
$454k
Studying Epigenetic Dysregulation in Down Syndrome Using Fluorescent Reporter Cell LinesR03NS126864 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZELDICH, ELLA · 2022 to 2023
$165k
NIA NIH HHS R21 AG080269NIA NIH HHS RF1 AG088529NINDS NIH HHS R03 NS126864NINDS NIH HHS R21 NS125469
6 · The paper itself

Abstract

Cortical organoids (COs) represent a powerful

Indexed as

assembloidsCLARITYneuronal activityorganoidsorganoid vascularizationtissue clearingtransplanted organoidsxenotranplantations

Identifiers

PMID42582357
PMCPMC13457730

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.