ArticleFrontiers in veterinary science2026
Evaluation of serologic assays for detection and quantification of influenza antibodies in milk samples from H5N1 highly pathogenic avian influenza virus infected dairy cows.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Since the confirmation of H5N1 HPAI virus in US dairy cattle on March 25, 2024, the bovine HPAI outbreak has continued with more than 1,000 confirmed herds in 19 states reported as of April 2, 2026. To ensure ongoing monitoring of HPAI spread, additional serologic assays have been evaluated to complement existing commercial ELISAs and molecular tools that underpin current epidemiological approaches. We previously established an N1 antibody-specific neuraminidase inhibition (NI)-enzyme linked lectin assay (ELLA) for DIVA (differentiation of infected from vaccinated animals) surveillance to detect H5N1 infection in vaccinated poultry with inactivated heterologous NA subtype (H5N9) vaccine. In this study, we applied NI-ELLA for the detection and quantification of N1 antibody in individual (
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