Evidence map›Paper›PMID 42582020›Full record

ReviewFrontiers in cellular neuroscience2026

Skin innervation and its

Émilie Genin, Lucile Guerber, Elodie Aymard, Jacques Leng, Joëlle Amédée, Alexis Desmoulière, François Berthod

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Émilie GeninLOEX, CHU de Quebec - Laval University Research Center and Department of Surgery, Faculty of Medicine, Laval University, Quebec City, QC, Canada.
Lucile GuerberSILAB, Saint-Viance, France.
Elodie AymardSILAB, Saint-Viance, France.
Jacques LengLaboratory of the Future (UMR 5258), Syensqo, CNRS, University of Bordeaux, Pessac, France.
Joëlle AmédéeBIOTIS, Inserm U1026, University of Bordeaux, Bordeaux, France.
Alexis DesmoulièreNeuropathies and Therapeutic Innovations (UR 20218), Faculties of Medicine and Pharmacy, University of Limoges, Limoges, France.
François BerthodLOEX, CHU de Quebec - Laval University Research Center and Department of Surgery, Faculty of Medicine, Laval University, Quebec City, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin innervation consists of myelinated Aβ fibers connected to sensory corpuscles and responsible for the sense of touch, and of free nerve endings including myelinated Aδ fibers and unmyelinated C fibers, that detect temperature and transmit pain signals, in addition to induce neurogenic inflammation through the release of neuropeptides. Moreover, the ability of skin innervation to detect pathogens that trigger or modulate immune reactions, such as TH1, TH2, or TH17 responses, has recently been identified, further growing interest in studying these neuroimmune interactions in the context of skin diseases. To this end, increasing efforts are being devoted to the development of

Indexed as

CGRPneuroinflammationneuropeptidesorgan-on-chipsubstance Ptissue engineering

Identifiers

PMID42582020
PMCPMC13457020

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.