ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
The relation between cardiovascular calcifications and diffuse idiopathic skeletal hyperostosis.
Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
introductionDiffuse idiopathic skeletal hyperostosis (DISH) has been associated with vascular calcifications, but data are inconclusive. We aimed to assess the association between DISH and calcifications of the coronaries, thoracic aorta, aortic valve, and mitral annulus/valve.
methodsA total of 3514 male individuals with current or past smoking behavior who underwent chest computed tomography (CT) from the NELSON lung cancer screening trial were included. Calcification volumes were quantified on chest CT using in house developed automatic validated software. DISH presence was assessed visually according to Resnick criteria. Associations were evaluated with multivariate linear and logistic regression models.
resultsDISH was present in 241 subjects (6.9%). Subjects with DISH had higher coronary calcification (median 402 mm
conclusionWe observed an independent relationship between DISH and thoracic aortic and aortic valve calcifications, but not with coronary artery calcifications and mitral valve calcifications.
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