Evidence map›Paper›PMID 42580843›Full record

Observational studyOpen heart2026

Complete versus incomplete coronary revascularisation in patients undergoing PCI after TAVI.

Carlo Andrea Pivato, Nicole Fontana, Leon Gramss, Emanuele Di Angelantonio, Francesca Ieva, Cosmo Godino, Masaaki Nakase, Karsten Hug, Tobias Andreas Rheude, Antonio Jesús Muñoz-García and 23 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Open heart, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Carlo Andrea PivatoIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy.ORCID http://orcid.org/0000-0001-5195-8815
Nicole FontanaHuman Technopole, Milan, Lombardy, Italy.
Leon GramssIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy.
Emanuele Di AngelantonioHuman Technopole, Milan, Lombardy, Italy.
Francesca IevaHuman Technopole, Milan, Lombardy, Italy.
Cosmo GodinoCardio-Thoracic-Vascular Department, San Raffaele Hospital, Milano, Italy.
Masaaki NakaseDepartment of Cardiology, Inselspital University Hospital, Bern, Switzerland.ORCID http://orcid.org/0000-0002-5359-8494
Karsten HugDepartment of Cardiology, Technical University of Munich School of Medicine, Munich, BY, Germany.
Tobias Andreas RheudeDepartment of Cardiology, German Heart Centre Munich, Munich, BY, Germany.
Antonio Jesús Muñoz-GarcíaDepartment of Cardiology, University Hospital Virgen de la Victoria, Málaga, Spain.
Victor Alfonso Jimenez DiazDepartment of Interventional Cardiology, Vigo University Hospital Group, Vigo, Spain.
Alfonso IelasiCardio-Thoracic, Istituto Clinico Sant'Ambrogio, Milano, Italy.
Marco BarbantiDivision of Cardiology, Università degli Studi di Enna 'Kore', Enna, Sicily, Italy.
Giuliano CostaDepartment of Cardiology, University Hospital System Gaspare Rodolico, San Marco, Catania, Sicily, Italy.ORCID http://orcid.org/0000-0003-3770-8988
Angelo AnzuiniMater Domini Hospital, Castellanza, Lombardy, Italy.
Giorgio QuadriDepartment of Interventional Cardiology, Azienda Ospedaliera Ordine Mauriziano di Torino, Turin, Piedmont, Italy.
Diego Lopez-OteroUniversity Hospital of Santiago de Compostela Servicio de Cardiología, Santiago De Compostela, Spain.
Philippe GarotInstitut Cardiovasculaire Paris Sud, Massy, Île-de-France, France.
Loredana BucciarelliInternational Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, Universita degli Studi di Milano, Milan, Lombardy, Italy.
Jorn BrouwerDepartment of Cardiology, St Antonius Hospital, Nieuwegein, Utrecht, Netherlands.
Bernhard ReimersIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy.
Damiano RegazzoliIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy.
Luca TestaCardiology, San Donato Teaching Hospital IRCCS, San Donato Milanese, Lombardy, Italy.
Jorge Sanz-SanchezDepartment of Cardiology, La Fe University and Polytechnic Hospital, Valencia, Valencian Community, Spain.ORCID http://orcid.org/0000-0003-4991-6549
Daijiro TomiiDepartment of Cardiology, Inselspital University Hospital, Bern, Switzerland.ORCID http://orcid.org/0000-0002-4488-1335
Alaide ChieffoCardiology Unit, IRCCS San Raffaele Scientific Institute and Vita-Salute University, Milan, Italy.
Michael JonerDepartment of Cardiology, German Heart Centre Munich, Munich, BY, Germany.
Gennaro SardellaUmberto I Policlinico di Roma, Rome, Lazio, Italy.
Enrico CerratoInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Italy.
Luis Nombela-FrancoInterventional Cardiology, Hospital Clinico Universitario San Carlos, Madrid, Spain.ORCID http://orcid.org/0000-0003-3438-8907
Gianluigi CondorelliIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy.
Thomas PilgrimDepartment of Cardiology, Inselspital University Hospital, Bern, Switzerland.ORCID http://orcid.org/0000-0001-8721-4068
Giulio Giuseppe StefaniniIRCCS Humanitas Research Hospital, Rozzano, Lombardy, Italy giulio.stefanini@hunimed.eu.ORCID http://orcid.org/0000-0002-3558-6967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal revascularisation strategy for patients undergoing percutaneous coronary intervention (PCI) after transcatheter aortic valve implantation (TAVI) remains undefined. In particular, the prognostic impact of complete revascularisation (CR) versus incomplete revascularisation (ICR) in this setting is unknown.

aimsTo evaluate the long-term clinical outcomes of CR versus ICR in patients undergoing PCI after TAVI.

methodsWe analysed 447 patients from the multicentre, international Revascularization After Transcatheter Aortic Valve Implantation (REVIVAL) registry who underwent PCI after TAVI between 2008 and 2023. Patients were classified as CR or ICR according to the presence of residual significant stenosis following PCI. The primary endpoint was the 4-year incidence of major adverse cardiovascular events (MACE), a composite of cardiovascular death, myocardial infarction or stroke. The Kaplan-Meier method was used to estimate cumulative event rates, and a weighted Cox regression model employing an entropy balance approach was used to adjust for possible confounders.

resultsICR was achieved in 132 patients (29.5%) and CR in 315 patients (70.5%). The mean follow-up after PCI was 1065±904 days (1213±938 in the ICR group; 1002±883 in the CR group). The crude 4-year incidence of MACE was 35.0% with ICR and 34.7% with CR (HR 0.93, 95% CI 0.62 to 1.39, p=0.710). Adjusted analysis confirmed no significant difference (32.5% vs 34.1%; HR 1.01, 95% CI 0.62 to 1.64, p=0.971).

conclusionIn this registry, CR after TAVI was common but not associated with improved outcomes compared with ICR. These results support a selective rather than systematic pursuit of CR in elderly, high-risk post-TAVI patients.

Indexed as

Aortic Valve StenosisCoronary Artery DiseasePercutaneous Coronary InterventionRegistriesTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleFollow-Up StudiesHumansIncidenceMaleRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsAortic Valve StenosisCardiac CatheterizationCORONARY ARTERY DISEASEPercutaneous Coronary InterventionTranscatheter Aortic Valve Replacement

Identifiers

PMID42580843
PMCPMC13475604

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.