Evidence map›Paper›PMID 42580701›Full record

ArticleBone & joint research2026

Establishment of a human osteocyte model to reveal mechanisms of chronic Staphylococcus epidermidis bone and joint infections.

Claudia Siverino, Qi Sun, Lucian Bogdan Solomon, Thomas Fintan Moriarty, Gerald J Atkins

Abstract read
In one paragraph

Article in Bone & joint research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia SiverinoAO Research Institute, Davos, Switzerland.ORCID 0000-0002-4845-1922
Qi SunBiomedical Orthopaedic Research Group, Discipline of Orthopaedic and Trauma Research, School of Medicine, College of Health, Adelaide University, Adelaide, Australia.ORCID 0000-0003-4826-6724
Lucian Bogdan SolomonBiomedical Orthopaedic Research Group, Discipline of Orthopaedic and Trauma Research, School of Medicine, College of Health, Adelaide University, Adelaide, Australia.ORCID 0000-0001-6254-2372
Thomas Fintan MoriartyAO Research Institute, Davos, Switzerland.ORCID 0000-0003-2307-0397
Gerald J AtkinsBiomedical Orthopaedic Research Group, Discipline of Orthopaedic and Trauma Research, School of Medicine, College of Health, Adelaide University, Adelaide, Australia.ORCID 0000-0002-3123-9861

Funding

AO TraumaNational Health and Medical Research Council of AustraliaSwiss National Science Foundation
6 · The paper itself

Abstract

Aims: Chronic bone and joint infections caused by Methods: The SaOS2 human osteosarcoma cell line was differentiated into osteoblast-like (SaOS2-OB) and osteocyte-like (SaOS2-OY) stages and infected with four Results: Lysostaphin was ineffective against all four Conclusion: We report the first model of intracellular

Identifiers

PMID42580701
PMCPMC13461255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.