ReviewScience progress
Can we rebuild what has been taken? A narrative review of biological and functional consequences of hamstring tendon harvest in ACL surgery.
Review in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Significant variability in limb symmetry across four different knee flexion strength tests after anterior cruciate ligament reconstruction.Journal of experimental orthopaedics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This narrative review aimed to summarize the consequences of hamstring tendon (HT) harvest for anterior cruciate ligament reconstruction (ACLR), with reference to tendon regeneration, knee flexor morphology, clinical assessment of knee flexion strength, and rehabilitation strategies for optimizing recovery. The available evidence suggests that the harvested semitendinosus (ST) and gracilis (GR) tendons regenerate in ∼70-86% of cases after ACLR. Despite tendon regeneration, ACLR with HT autograft results in morphological alterations in both the ST and GR. These changes include tendon elongation, proximal migration of the musculotendinous junction, muscle atrophy, shortened fascicles, and increased fatty infiltration, which may persist for several years after ACLR. Growing evidence also suggests that assessment of knee flexion strength after ACLR cannot rely on a single test position, and that knee flexion strength should be evaluated in both hip-flexed and hip-extended positions to provide a more comprehensive evaluation of the recovery. We propose that optimizing the recovery of knee flexion strength may benefit from a multifaceted approach: (1) early, symptom-guided initiation of isometric and low-load exercises to minimize early strength deficits, (2) progressive loading of the knee flexors across multiple hip-and knee-joint angles, including the seated leg-curl to promote a high ST activation, (3) subsequent incorporation of eccentric loading as part of progressive strengthening strategies, with the aim of enhancing ST and GR muscle volumes and fascicle lengths, and (4) strength assessments across multiple hip and knee-joint positions to monitor recovery, as testing in a seated position may underestimate residual deficits in the ST and GR.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.