ArticleJournal of the Egyptian National Cancer Institute2026
Uterine transposition for fertility preservation prior to pelvic irradiation: an initial Egyptian case series.
Article in Journal of the Egyptian National Cancer Institute, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRecently, uterine transposition has been proposed as a novel technique for fertility preservation in young females undergoing radiation therapy for pelvic malignancies. PATIENTS AND
methodsThis is an interventional pilot study including six female patients with pelvic malignancies planned to receive pelvic radiation aiming at preserving their fertility after a multidisciplinary team decision to have uterine transposition. Our study aims to assess the feasibility of this novel technique.
resultsSix patients underwent uterine transposition. Three of them were done through open technique, with successful repositioning. The other three patients underwent laparoscopic uterine transposition, one of them underwent repositioning and still receiving chemotherapy for Ewing's sarcoma, the other two patients are still receiving radiation therapy after transposition. Unfortunately, one of them died of disease and adjuvant therapy complications four months after laparoscopic uterine transposition.
conclusionUterine transposition is a feasible procedure with safe outcomes. The preliminary results carry a promising hope for better fertility preservation in young patients undergoing radiation for pelvic malignancies.
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