Evidence map›Paper›PMID 42579200›Full record

ArticleAntonie van Leeuwenhoek2026

Pediococcus acidilactici JUFB as a probiotic antibiofilm adjunct against Enterococcus faecalis in persistent endodontic infections.

Arpitha Somayaji, R Manjushree, Sushma S Murthy, Mohammed Aman

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Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arpitha SomayajiDepartment of Microbiology and Botany, School of Sciences, Jain (Deemed to Be University), JC Road, Bangalore, Karnataka, 560002, India.
R ManjushreePrasad's Dental Care, Bangalore, Karnataka, India.
Sushma S MurthyDepartment of Microbiology and Botany, School of Sciences, Jain (Deemed to Be University), JC Road, Bangalore, Karnataka, 560002, India.
Mohammed AmanDepartment of Microbiology and Botany, School of Sciences, Jain (Deemed to Be University), JC Road, Bangalore, Karnataka, 560002, India. mohammed@jainuniversity.ac.in.ORCID http://orcid.org/0000-0001-8688-350X

Funding

Jain (Deemed to be University) under Minor Research project JU/MRP/SOS/2/2022
6 · The paper itself

Abstract

Enterococcus faecalis remains a primary cause of persistent endodontic infections, persisting in root canals through robust biofilm formation and antimicrobial resistance. This study characterized clinical E. faecalis oral isolates and evaluated the comparative efficacy of conventional endodontic medicaments against the probiotic and antibiofilm potential of food derived Lactic Acid Bacteria (LAB). Clinical isolates (JUDS 01, JUDS 02, JUDS 03, JUSA 05) exhibited a high prevalence of ace, agg, cyl, and gelE virulence genes, demonstrating significant multidrug resistance. Among conventional treatments, TAP exhibited the notable antibacterial zones of inhibition (23 ± 1-24 ± 0.5 mm) and uniform, highly significant biomass reduction (p < 0.0001), whereas Ca(OH)2, NaOCl, and DAP completely failed to reduce mature biofilms (p > 0.05). Among the probiotic strains, Pediococcus acidilactici JUFB demonstrated great physiological stress tolerance, maintaining robust survival under lethal acid conditions (OD

Indexed as

AntibiosisBiofilmsEnterococcus faecalisGram-Positive Bacterial InfectionsPediococcus acidilacticiPersistent InfectionProbioticsAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsVirulence FactorsAnti-Bacterial AgentsVirulence FactorsAntibiotic resistanceBiofilm inhibitionE. faecalisPathogenicityVirulence genes

Identifiers

PMID42579200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.