ArticleSleep & breathing = Schlaf & Atmung2026
Prevalence of restless genital syndrome among pregnant women presenting with vaginal discharge and genital symptoms.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo determine the prevalence of restless genital syndrome (RGS) among pregnant women presenting with vaginal discharge or genital complaints and to evaluate the association between RGS and levels of anxiety and depression. The reported prevalence reflects a symptom-based clinical subgroup rather than that of the general pregnant population.
methodThis cross-sectional, questionnaire-based study included 305 pregnant women who presented at the Obstetrics Outpatient Clinic with vaginal discharge or other genital complaints during the second or third trimester of pregnancy. Sociodemographic characteristics were recorded, and all participants completed the Restless Genital Syndrome diagnostic questionnaire, the Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI).
resultsRGS symptoms were identified in 140 (45.9%) participants. As the study population consisted exclusively of pregnant women presenting with genital complaints, this frequency should not be interpreted as representative of the general pregnant population. According to the BAI, severe anxiety levels were significantly higher in women with RGS than in those without RGS (p = 0.026). Mild depression, based on the BDI, was also significantly more frequent in the RGS group (p = 0.003). A significant positive correlation was found between anxiety and depression scores (r = 0.622, p < 0.001).
conclusionRGS symptoms were frequently observed among pregnant women presenting with genital complaints, such as discharge and itching. These symptoms were associated with higher levels of anxiety and depression. However, given the cross-sectional design and the symptom-based sample, these findings should be interpreted as associations rather than causal relationships. Clinicians evaluating pregnant women with genital discomfort should consider RGS in the differential diagnosis.
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