ArticleAntonie van Leeuwenhoek2026
Bioprospecting of cultivable actinobacteria from tropical peat swamp forest soil reveals Streptomyces with potent antimicrobial activity.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The rapid emergence of multidrug-resistant pathogens has become a major global health concern, highlighting the urgent need to discover new antimicrobial agents. Actinobacteria, particularly Streptomyces, are well known for their ability to produce diverse bioactive secondary metabolites with important pharmaceutical and agricultural applications. The purpose of this research was to isolate, characterize and evaluate the antimicrobial potential of actinobacteria isolated from tropical peat swamp forest soil. A total of 157 actinobacterial isolates were obtained and assigned to the genera Streptomyces, Microbispora, Microtetraspora, Micromonospora and Planosporangium. Preliminary antimicrobial screening revealed that 81 isolates (51.59%) exhibited inhibitory activity against at least one of the tested pathogens. Crude extracts from 17 selected isolates demonstrated antimicrobial activity with minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) values ranging from 0.024 to 12.50 mg mL
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