ArticleBulletin of environmental contamination and toxicology2026
In Vitro Toxicity Assessment of Tire-related Chemicals in Cells from Diverse Fish Species.
Article in Bulletin of environmental contamination and toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Urban stormwater runoff introduces tire‑related contaminants such as 6PPD‑quinone (6PPD‑Q), which has been shown to exhibit acute toxicity in some salmonid species, although the underlying toxic mechanisms remain incompletely understood. To expand in vitro toxicological assessments, we evaluated the cytotoxicity of 3,4‑dichloroaniline and 6PPD‑quinone using six fish‑derived cell lines from salmonids and phylogenetically distant species, based on nominal concentrations at the time of addition. Among these cell lines, CSE‑119 cells, which are derived from coho salmon, exhibited the highest sensitivity to 6PPD‑quinone (EC
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