Evidence map›Paper›PMID 42578758›Full record

ArticleActa dermato-venereologica2026

Quality of Life, Mental Health and Executive Function in Individuals with Basal Cell Naevus Syndrome.

Karianne H Brandtzæg, Charlotte Von der Lippe, Ina S Almdahl, Anvor Rossow, Ragnhild S Falk, Petter Gjersvik, Kristin H Hortemo, Solrun Sigurdardottir

Abstract read
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In one paragraph

Article in Acta dermato-venereologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karianne H BrandtzægInstitute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Dermatology, Oslo University Hospital, Oslo, Norway. kahaga@ous-hf.no.ORCID 0000-0002-6756-8886
Charlotte Von der LippeDepartment of Medical Genetics, Telemark Hospital, Skien, Norway.ORCID 0000-0003-3176-0160
Ina S AlmdahlNorwegian Centre for Rare Diseases, Unit Gaustad, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-6070-4921
Anvor RossowNorwegian Centre for Rare Diseases, Unit Oral Health, Lovisenberg Diaconal Hospital, Oslo, Norway.
Ragnhild S FalkOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-8398-3492
Petter GjersvikInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0002-3596-9829
Kristin H Hortemo *Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Dermatology, Oslo University Hospital, Oslo, Norway.ORCID 0009-0008-4423-6871
Solrun Sigurdardottir *Norwegian Centre for Rare Diseases, Unit Gaustad, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-7194-3570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell naevus syndrome (BCNS) is a rare genetic disorder characteriszed by multiple basal cell carcinomas, as well as different extracutaneous tumours, cysts and abnormalities. Research on health-related quality of life (HRQoL) and mental health in BCNS is limited. This cross-sectional study included 62 individuals ≥18 years diagnosed with BCNS. Clinical and genetic data were collected, and five5 validated questionnaires were used to assess self-reported HRQoL, psychological distress, fatigue, pain and everyday executive functioning. Median regression analyses were conducted to identify factors associated with HRQoL. Independent samples t-tests and one proportion z-tests were conducted to compare the BCNS group with the general population. Individuals with BCNS reported lower HRQoL compared with the general population. Elevated anxiety symptoms were observed in 14 individuals (24%). The proportion of individuals reporting everyday executive deficits was higher in the BCNS group compared with the general population. Engagement in employment or higher education was associated with better physical and mental HRQoL, whereas symptoms of anxiety and everyday executive deficits were associated with reduced mental HRQoL. Findings highlight mental health challenges in BCNS. Routine screening for anxiety and executive functioning is suggested as essential steps in identifying those at risk and provideproviding timely psychological support.

Indexed as

Basal Cell Nevus SyndromeExecutive FunctionMental HealthQuality of LifeSkin NeoplasmsAdolescentAdultAgedAnxietyCross-Sectional StudiesFatigueFemaleHumansMaleMiddle AgedPsychological Distress

Identifiers

PMID42578758
PMCPMC13459420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.