Evidence map›Paper›PMID 42578545›Full record

ArticleJournal of anatomy2026

Regional specialization of upper-layer inhibitory interneuron organization in the human prefrontal cortex.

Ivan Banovac, Marija Baković, Davor Mayer, Dora Sedmak, Zdravko Petanjek

Abstract read
In one paragraph

Article in Journal of anatomy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ivan BanovacDepartment of Anatomy and Clinical Anatomy, University of Zagreb School of Medicine, Zagreb, Croatia.ORCID https://orcid.org/0000-0001-8233-7405
Marija BakovićDepartment of Forensic Medicine, University of Zagreb School of Medicine, Zagreb, Croatia.
Davor MayerDepartment of Forensic Medicine, University of Zagreb School of Medicine, Zagreb, Croatia.
Dora SedmakDepartment of Anatomy and Clinical Anatomy, University of Zagreb School of Medicine, Zagreb, Croatia.ORCID https://orcid.org/0000-0001-9910-1781
Zdravko PetanjekDepartment of Anatomy and Clinical Anatomy, University of Zagreb School of Medicine, Zagreb, Croatia.ORCID https://orcid.org/0000-0001-5019-4198

Funding

Hrvatska Zaklada za Znanost IP-2022-10-8493
6 · The paper itself

Abstract

GABAergic interneurons play a central role in shaping cortical microcircuit function, yet the anatomical organization of major interneuron populations across different subdivisions of the human prefrontal cortex remains poorly characterized. The present study examined the laminar distribution and regional organization of major GABAergic interneuron populations in the dorsal (Brodmann area 9) and ventral (Brodmann area 14r) portions of the human prefrontal cortex. Postmortem human prefrontal cortex tissue from five normotypical adult male brains was analysed using the following molecular markers: calretinin (CR), parvalbumin (PV), calbindin (CB), and somatostatin (SOM). Double-labelling immunofluorescence was used to assess overlaps between different GABAergic interneuron populations, and RNAscope in situ hybridization was used to confirm their neurotransmitter phenotype. All analysed populations demonstrated a GABAergic molecular phenotype. CR

Indexed as

calretinincortical microcircuitryGABAergic interneuronshuman prefrontal corteximmunohistochemistry

Identifiers

PMID42578545
PMCPMC13459391

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.