Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Sören BrandenburgHeart Research Center Göttingen, Department of Cardiology & Pneumology, University Medical Center Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0001-5148-0997
Dennis UhlenkampHeart Research Center Göttingen, Department of Cardiology & Pneumology, University Medical Center Göttingen, Göttingen, Germany.
Bianca MeyerDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Clara SandmannDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Nicole HerzogDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Julia GroßDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Hugo A KatusDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Stephan E LehnartHeart Research Center Göttingen, Department of Cardiology & Pneumology, University Medical Center Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0002-8115-3513
Christopher C GlembotskiDepartment of Internal Medicine and Translational Cardiovascular Research Center, University of Arizona College of Medicine - Phoenix, Phoenix, USA.ORCID https://orcid.org/0000-0002-1380-5073
Mirko VölkersDepartment of Cardiology, Angiology, and Pneumology, Heidelberg University Hospital, Heidelberg, Germany.
Shirin DoroudgarDepartment of Internal Medicine and Translational Cardiovascular Research Center, University of Arizona College of Medicine - Phoenix, Phoenix, USA.ORCID https://orcid.org/0000-0001-8867-6010
Funding
Non-canonical ERAD as a Regulator of Cardiac HypertrophyR01HL157027 · NHLBI · UNIVERSITY OF ARIZONA · PI GLEMBOTSKI, CHRIS · 2022 to 2025
$2.6M
Post-Transcriptional Regulation of Gene Expression by Ribosome-Binding Protein 1R01HL170223 · NHLBI · UNIVERSITY OF ARIZONA · PI Shirin Doroudgar · 2024 to 2026
$2.2M
Roles for endoplasmic reticulum associated degradation (ERAD) in Myocardial ProteostasisR01HL174576 · NHLBI · UNIVERSITY OF ARIZONA · PI Chris Glembotski · 2024 to 2026
$2.1M
ATF6 as a Regulator of Atrial Myocyte ER ProteostasisR01HL178630 · NHLBI · UNIVERSITY OF ARIZONA · PI Chris Glembotski · 2026 to 2026
$1.6M
DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/MannheimGerman Cardiac SocietyGerman Centre for Cardiovascular ResearchGerman Heart FoundationNHLBI NIH HHS R01 HL157027NHLBI NIH HHS R01 HL170223NHLBI NIH HHS R01 HL174576NHLBI NIH HHS R01 HL178630NIH HHS HL157027NIH HHS HL170223NIH HHS HL174576NIH HHS HL178630University of Arizona College of Medicine Phoenix Translational Cardiovascular Research CenterUniversity of Arizona Health Sciences
6 · The paper itself
Abstract
The endoplasmic reticulum (ER) is the primary site for the synthesis and folding of membrane and secretory proteins, which together comprise a large fraction of the total protein output in mammalian cells. Striated muscle cells contain a specialized membrane system, the sarcoplasmic reticulum (SR), which regulates calcium homeostasis and contraction. However, the biochemical and physiological relationship between the ER and SR, as well as the extent to which both compartments contribute to protein synthesis, remain incompletely understood. Quantification of ER- and SR-associated proteins in isolated ventricular cardiac myocytes revealed that the relative abundance of ER/SR-resident protein quality control components and ribosomes decreased during postnatal maturation, whereas SR-associated Ca
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes. · full record | OpenQuestion