Evidence map›Paper›PMID 42578462›Full record

ArticleeLife2026

A dual role for PGLYRP1 in host defense and immune regulation during

David M Rickert, Sasha Cardozo, Nicholas Carbonetti, William E Goldman, Karen M Scanlon, Ciaran Skerry

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

David M RickertDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.ORCID https://orcid.org/0009-0002-7229-0046
Sasha CardozoDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.ORCID https://orcid.org/0000-0003-1608-7086
Nicholas CarbonettiDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.
William E GoldmanDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, United States.ORCID https://orcid.org/0000-0002-1551-6718
Karen M ScanlonDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.ORCID https://orcid.org/0000-0002-5300-8749
Ciaran SkerryDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, United States.ORCID https://orcid.org/0009-0009-3511-7472

Funding

Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
Pertussis inflammation is mediated by a balance between peptidoglycan recognition proteins-1 and -4R01AI167947 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Ciaran Skerry · 2022 to 2026
$2.1M
National Institute of Allergy and Infectious Diseases R01AI 167947National Institute of Allergy and Infectious Diseases T32 AI095190NIAID NIH HHS R01 AI167947NIAID NIH HHS T32 AI095190
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bordetella pertussisCarrier ProteinsHost-Pathogen InteractionsWhooping CoughAnimalsImmunity, InnateInnate Immunity RecognitionMiceMice, KnockoutCarrier Proteinspeptidoglycan recognition proteinBordetella pertussisinfectious diseaseinflammationmicrobiologypeptidoglycanpertussisPGLYRPPGLYRP1

Identifiers

PMID42578462
PMCPMC13461146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.