ArticleEnvironmental epidemiology (Philadelphia, Pa.)2026
Associations of cognitive function with recent and cumulative per- and polyfluoroalkyl substances exposure in firefighters.
Article in Environmental epidemiology (Philadelphia, Pa.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This pilot study aimed to examine associations between recent occupational exposure to per- and polyfluoroalkyl substances (PFAS) and domain-specific cognitive performance and explore whether cumulative perfluorooctane sulfonic acid (PFOS) modified these associations. Methods: Sixty-five actively serving firefighters in Central Texas (June 2023-March 2025) participated. Recent exposure was assessed using total concentrations (pg/µl) of perfluorobutanoic acid, perfluorobutane sulfonic acid, and PFOS measured in single post-incident wash-water samples from three sites (June-August 2024), with site-specific results extrapolated to all firefighters at each site. Cumulative exposure was measured using PFOS concentrations (pg/µl) in whole blood collected from February to March 2025. Cognitive outcomes included standardized Results: After adjustment, each doubling of cumulative PFOS corresponded to an estimated 11.1-point decline in processing speed (β = -1.07, 95% confidence interval = -1.59, -0.55, Conclusion: PFAS exposure may differentially relate to cognitive domains in firefighters. Cumulative PFOS was associated with reduced processing speed and modified the impact of recent exposure. These preliminary findings warrant confirmation in larger studies and highlight the need to evaluate exposure mitigation strategies, including decontamination practices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.