Evidence map›Paper›PMID 42578161›Full record

ArticleCase reports in oncology

Germline HOXB13 G84E Variant in a Patient with Gastric and Prostate Cancer: A Case Report and Literature Review.

Anne-Murielle Hollinger, Saskia Schlootz, Manuela Poretti, Lorenz Frehner, Till Lerch, Muriel Fluri, Saskia Hussung, Javier Sanz, Maurus Locher, Christiane Zweier and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne-Murielle HollingerDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.
Saskia SchlootzDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.
Manuela PorettiDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.
Lorenz FrehnerDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.
Till LerchInstitute of Diagnostic, Interventional and Paediatric Radiology, University Hospital of Bern, Bern, Switzerland.
Muriel FluriDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.
Saskia HussungDepartment of Medical Oncology and Hematology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Javier SanzDepartment of Human Genetics, University Hospital of Bern, University of Bern, Bern, Switzerland.
Maurus LocherDepartment of Human Genetics, University Hospital of Bern, University of Bern, Bern, Switzerland.
Christiane ZweierDepartment of Human Genetics, University Hospital of Bern, University of Bern, Bern, Switzerland.
Dilara AkhoundovaDepartment of Medical Oncology, University Hospital of Bern, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Case Presentation: We present a case of a 50-year-old male patient with locally advanced gastric adenocarcinoma who was later diagnosed with prostate cancer. Patient's family history was notable for several malignancies, including endometrial carcinoma, thyroid cancer, and breast cancer on the same side of the family. Germline testing was negative for gastric cancer susceptibility genes but identified a germline HOXB13 G84E mutation. Conclusion: To the best of our knowledge, this is the first case report of a patient with a germline

Indexed as

Cancer predispositionCase reportGermline pathogenic variantHereditary cancer syndromeHOXB13Prostate cancer

Identifiers

PMID42578161
PMCPMC13456669

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