ArticleInternational journal of surgery case reports2026
Pathological fracture of the tibia after bone biopsy for Erdheim-Chester disease: a case report.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by the invasion of CD68 Case report: Radiographs of both knees revealed diffusely sclerotic bone lesions in the metaphyses of the tibia and femur. Magnetic resonance imaging revealed that these lesions had hypointense signals and slightly hyperintense signals on the T1-weighted image. The sagittal fat-saturated T2-weighted image showed irregular enhancement within the lesion in the right tibia. A tibial biopsy showed infiltration of foamy CD68 Conclusion: This case suggests that additional plate fixation immediately after a bone biopsy may be required to prevent pathological fractures. Further research about the bone strength of patients with ECD, as well as pathological fractures after tibia biopsy for ECD, needs to be investigated.
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