ArticleAnnals of maxillofacial surgery
Intralesional Bleomycin in the Management of Low-flow Vascular Malformations - A Case Report.
Article in Annals of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Rationale: Low-flow vascular malformations (LFVMs) of the orofacial region are rare congenital vascular anomalies caused by aberrant development of venous and lymphatic channels, leading to slow or stagnant blood flow. This report highlights the successful management of LFVMs of buccal mucosa using ultrasound-guided bleomycin sclerotherapy. Patient Concerns: A 37-year-old female presented with a 5-year history of progressive, painless swelling of the left buccal mucosa. Diagnosis: Clinical and radiological evaluation, including computed tomography (CT) angiography, confirmed a LFVM supplied by the left facial artery with venous drainage into the retromandibular vein. Treatment: The patient underwent three weekly sessions of ultrasound-guided intralesional bleomycin sclerotherapy (15 IU in 10 mL sterile water). Outcomes: One-year follow-up CT angiography showed minimal residual tissue with no recurrence and a 70% reduction in lesion size was noted. Take-away Lessons: Ultrasound-guided bleomycin sclerotherapy is a safe, minimally invasive and effective treatment for LFVM in cosmetically sensitive facial regions.
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