Evidence map›Paper›PMID 42577887›Full record

ArticleAcademia mental health & well-being2026

What outcomes matter in recovery from depression? A pilot study of young adults.

Jeffrey A Lam, Norah Mulvaney-Day, Alexandra R Dobbins, Rajendra Aldis, Ishan Pasricha, Hermioni L Amonoo, Ana M Progovac

Abstract read
In one paragraph

Article in Academia mental health & well-being, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey A LamDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Norah Mulvaney-DayDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Alexandra R DobbinsDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Rajendra AldisDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Ishan PasrichaDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Hermioni L AmonooDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Ana M ProgovacInstitute for Excellence in Health Equity, New York University Grossman School of Medicine, New York, NY, USA.

Funding

Understanding the Role of Trauma Over the Lifecourse in Order to Improve Trauma-informed TreatmentP50MH126283 · NIMH · CAMBRIDGE HEALTH ALLIANCE · PI COOK, BENJAMIN LE, WANG, PHILIP S · 2021 to 2024
$6.6M
NIMH NIH HHS P50 MH126283
6 · The paper itself

Abstract

Introduction: "Positive" outcomes such as flourishing and personal recovery are important predictors of physical health, mental illness, quality of life, and all-cause mortality. However, behavioral health outcome measures often emphasize symptom reduction, while overlooking "positive" outcomes. The objective of this study is to describe (1) the outcomes most important to individuals with major depressive disorder (MDD) and (2) "positive" outcomes and psychiatric symptoms in a real-world sample of young adults with MDD. Materials and methods: Forty-three participants aged 18-35 with a diagnosis of MDD receiving outpatient behavioral health treatment in an urban safety-net psychiatry department completed online surveys identifying factors most important to recovery and standardized measures of flourishing, personal recovery, functioning, and symptoms of depression and anxiety. Results: Most participants (61.9%) had high symptoms of depression (Patient Health Questionnaire-8 (PHQ-8) ≥ 10), 16.7% were flourishing (Flourishing Scale ≥ 48), and 41.9% had high personal recovery (Brief INSPIRE-O ≥ 50). Factors ranked as "most important" for personal recovery included coping well with stressful events (39.5%), functioning well (34.9%), and having hopes and dreams for the future (30.2%). Notably, among individuals with low depressive symptoms, 60.0% reported low flourishing and 31.3% reported low personal recovery. Conclusions: Individuals with MDD value a diverse range of outcomes, and exhibit a large variation in levels of depressive symptoms and characteristics of "positive" mental health. Aligning outcome tracking with patient-defined goals may provide a more comprehensive understanding of overall mental health.

Indexed as

flourishingmajor depressive disorderpatient-centered outcomespersonal recoverypsychological well-being

Identifiers

PMID42577887
PMCPMC13455757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.