ArticlePolish journal of radiology2026
Quantitative CT texture analysis of the mandibular condyle in medication-related osteonecrosis of the jaw.
Article in Polish journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: In this study, we quantitatively assessed the involvement of the mandibular condyle in patients with medication-related osteonecrosis of the jaw (MRONJ) based on computed tomography (CT) texture analysis. Material and methods: We analyzed CT scans obtained between April 2020 and March 2023, from 31 patients (7 males and 24 females) with MRONJ. We extracted 279 radiomic features from regions of interest defined on the affected and control sides. These features were analyzed using MaZda version 4.6.2.0. Using Fisher's coefficient, 10 of these features were selected for analysis. The selected features were compared between the affected and control sides using the paired Results: All selected radiomics features, which were texture features of the mandibular condylar bone marrow, showed significant differences between the affected and control sides in patients with MRONJ ( Conclusions: These findings suggested that microstructural changes, not easily detected on visual inspection, may occur in the trabecular structure of the affected mandibular condyle in patients with MRONJ. Therefore, the impact of the disease on the temporomandibular joint should be considered in MRONJ.
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