Evidence map›Paper›PMID 42577640›Full record

ArticleClinical, cosmetic and investigational dermatology2026

Molecular Evidence for

Zining Xu, Lingbo Bi, Ziyi Wang, Yujun Sheng, Yong Cui

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zining XuChina-Japan Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0009-0006-0531-3382
Lingbo BiGraduate School, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Ziyi WangDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, People's Republic of China.
Yujun ShengDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, People's Republic of China.
Yong CuiChina-Japan Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pachyonychia congenita tarda (PCT) is a rare late-onset variant of pachyonychia congenita (PC), with its nosological status remaining controversial due to limited molecular confirmation in adult-onset cases. We report a 57-year-old Chinese woman who presented with a four-year history of progressive, painful thickening of all 20 nails, accompanied by mild palmoplantar keratoderma. Repeated mycological examinations were negative, and no clinical improvement was observed after prolonged antifungal therapy. Familial segregation analysis could not be performed because biological samples from relatives were unavailable, and the patient reported no known affected relatives. Whole-exome sequencing (WES), followed by Sanger confirmation, identified a heterozygous missense variant in

Indexed as

case reportectodermal dysplasiagenodermatosesnail disorders

Identifiers

PMID42577640
PMCPMC13454865

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.