ArticleJournal of inflammation research2026
Inflammatory Mediation of the Association Between Latent Clinical Phenotypes and Multidimensional Outcomes in Pediatric Community-Acquired Pneumonia.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: To analyse the association between latent clinical phenotypes and multidimensional outcomes in pediatric community-acquired pneumonia and evaluate the role of inflammation in this relationship. Methods: This retrospective observational cohort study included 700 hospitalized children with community-acquired pneumonia at Shanghai Sixth People's Hospital from January 1, 2023 to June 30, 2025. Latent class analysis was performed to identify clinical phenotypes. We assessed the association between community-acquired pneumonia subgroups and multidimensional outcomes. Joint effects of community-acquired pneumonia subgroups and c-reactive protein/interleukin-6 on multidimensional outcomes were investigated. Associations between individual respiratory pathogens and multidimensional outcomes were also assessed. Mediation analyses were conducted to examine the role of c-reactive protein/interleukin-6 in the association between clinical phenotypes/pathogens and multidimensional outcomes. Results: Older-full term- Conclusion: The older-full term-
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