ArticleFrontiers in immunology2026
CD73 is associated with glycolysis related metabolic programs and CD8
Eriko Katsuta, Aarohan Mukherjee Burma, Eito Nakagawa, Ken Oh, Tao Dai, Subhamoy Dasgupta, Kazuaki Takabe, Daisuke Ban
Abstract read
In one paragraphArticle in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Eriko KatsutaDepartment of Hepatobiliary and Pancreatic Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Aarohan Mukherjee BurmaDepartment of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Eito NakagawaDepartment of Hepatobiliary and Pancreatic Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Ken OhDepartment of Hepatobiliary and Pancreatic Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Tao DaiDepartment of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Subhamoy DasguptaDepartment of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Kazuaki TakabeDepartment of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Daisuke BanDepartment of Hepatobiliary and Pancreatic Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Funding
Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6MDetermining the Impact of Metabolic Adaptations on the Immune-Tumor Microenvironment in Metastatic Breast CancerR01CA285707 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Scott I. Abrams, Subhamoy Dasgupta · 2025 to 2026
$1.4MNCI NIH HHS P30 CA016056NCI NIH HHS R01 CA285707
6 · The paper itselfAbstract
CD73 is an enzyme that generates extracellular adenosine and has been implicated in tumor-associated immune suppression, but its biological and clinical significance in pancreatic ductal adenocarcinoma (PDAC) remains incompletely understood. We investigated the prognostic relevance and biological functions of CD73 in PDAC using transcriptomic analyses,
Indexed as
5'-NucleotidaseCarcinoma, Pancreatic DuctalCD8-Positive T-LymphocytesGlycolysisPancreatic NeoplasmsAnimalsCell Line, TumorFemaleGene Expression Regulation, NeoplasticGPI-Linked ProteinsHumansLymphocytes, Tumor-InfiltratingMetabolic ReprogrammingMice5'-NucleotidaseGPI-Linked ProteinsNT5E protein, humanCD73glycolysishypoxiaimmune suppressionpancreatic ductal adenocarcinoma
Identifiers
PMID42577400
PMCPMC13454112
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