Evidence map›Paper›PMID 42577376›Full record

ArticleThe Lancet regional health. Europe2026

Trends in type 2 diabetes incidence and BMI at diagnosis by age, sex, and ethnicity, 2011-2024: a population-based analysis of the English National Diabetes Audit.

Naomi Holman, Jackie O'Keefe, Edward Gregg, Garry Daniel Tan, Kamlesh Khunti, Jonathan Valabhji, Chirag Bakhai, Clare Hambling, Bob Young, Shivani Misra

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Article in The Lancet regional health. Europe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Naomi HolmanSchool of Public Health, Imperial College, London, UK.
Jackie O'KeefeSchool of Public Health, Imperial College, London, UK.
Edward GreggSchool of Population Health, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Garry Daniel TanOxford Centre for Diabetes, Endocrinology & Metabolism, Oxford University Hospitals, Oxford, UK.
Kamlesh KhuntiDiabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
Jonathan ValabhjiDivision of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Chirag BakhaiDiabetes Programme, NHS England, London, UK.
Clare HamblingDiabetes Programme, NHS England, London, UK.
Bob YoungDiabetes UK, London, UK.
Shivani MisraDivision of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Early-onset type 2 diabetes is associated with aggressive disease progression, long-term health burden and reduced life expectancy. Trends in incidence have not been comprehensively described. Methods: Using data from the English National Diabetes Audit, age-standardised incidence rates for adults with type 2 diabetes were calculated by age, sex, and ethnicity between 2011 and 2024. Poisson regression models were created to study incidence over time. Annual change in median BMI within 26 weeks of diagnosis were calculated. Findings: Age-standardised incidence increased among adults aged 20-29 years (RR 1.021 [95% CI 1.017-1.026] per year in males, 1.030 [1.026-1.034] in females) and 30-39 years (1.013 [1.012-1.015] in males, 1.03 [1.028-1.032] in females). Incidence increased minimally in males aged 40-59 years (1.006 [1.005-1.006]), was rising in females (1.018 [1.017-1.019]) and declined in males and females aged 60-79 years (0.983 [0.983-0.984] in males, 0.985 in females 0.985 [0.984-0.985]). Increasing incidence in young adults were observed in all sex and ethnicity subgroups except Asian males (20-39-years) but highest rates were in White females (30-39-years) and Black females (20-29). BMI at diagnosis increased in all subgroups over time but was highest in younger adults and higher in females than males. The annual change in younger adults was double that of older (20-29 year-old-males +0.17 kg/m Interpretation: Since 2011, incidence of type 2 diabetes has risen significantly in young adults across most ethnicity and sex subgroups (especially females) despite minimal changes or declining rates at older ages. This trend parallels greater increases in BMI-at-diagnosis in young people, highlighting a shift in disease burden and the urgent need for earlier prevention, and focused obesity interventions in early-life. Funding: Wellcome Trust.

Indexed as

Early-onset type 2 diabetesEpidemiologyEthnicityIncidenceType 2 diabetesYoung type 2 diabetes

Identifiers

PMID42577376
PMCPMC13453952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.