Evidence map›Paper›PMID 42577249›Full record

ArticleJTCVS techniques2026

Standardized femoral artery cannulation and ischemia-prevention protocol for minimally invasive cardiac surgery.

Shota Inoue, Kohei Nagashima, Mitsuru Yokoyama, Nariaki Nagaoka, Hiroshi Nakanaga, Chikara Ueki, Atsuhiko Sato, Shigefumi Matsuyama, Minoru Tabata

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Article in JTCVS techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Shota InoueDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Kohei NagashimaDepartment of Clinical Engineering, Toranomon Hospital, Tokyo, Japan.
Mitsuru YokoyamaDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Nariaki NagaokaDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Hiroshi NakanagaDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Chikara UekiDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Atsuhiko SatoDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Shigefumi MatsuyamaDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.
Minoru TabataDepartment of Cardiovascular Surgery, Toranomon Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: In minimally invasive cardiac surgery, femoral artery cannulation is widely used; however, it may cause lower-limb ischemia. We developed a standardized patient-selection strategy, a femoral artery-cannulation technique, and a structured ischemia-prevention protocol and evaluated their reproducibility and clinical effectiveness in preventing limb ischemia. Methods: We retrospectively analyzed 505 patients who underwent totally endoscopic minimally invasive cardiac surgery with femoral artery cannulation between June 2019 and July 2024. The arterial cannula was inserted with the proximal side hole directed dorsally and secured at a shallow depth to facilitate distal perfusion. Regional oxygen saturation of both lower limbs was continuously monitored. A >50% decrease in regional oxygen saturation triggered a stepwise protocol: increased cardiopulmonary bypass flow, topical papaverine hydrochloride solution, and, if unresolved, distal perfusion via a 6-Fr sheath. The incidences of clinical limb ischemia (need for distal perfusion or compartment syndrome) and a >50% decrease in regional oxygen saturation were evaluated, and risk factors for regional oxygen saturation decrease were identified. Results: No patients required distal perfusion or developed postoperative compartment syndrome. A >50% decrease in regional oxygen saturation occurred in 28 patients (5.5%), all of whom recovered without distal perfusion. Multivariate analysis identified smaller femoral artery diameter and low ejection fraction as independent risk factors for regional oxygen saturation decrease. Conclusions: A standardized patient-selection strategy combined with a femoral artery-cannulation technique and a structured ischemia-prevention protocol effectively prevented clinically significant limb ischemia without the need for distal perfusion in this cohort.

Indexed as

distal perfusionfemoral artery cannulationlower-limb ischemiaminimally invasive cardiac surgeryregional oxygen saturation

Identifiers

PMID42577249
PMCPMC13453796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.