Evidence map›Paper›PMID 42577141›Full record

ArticleFrontiers in medicine2026

Medicine 4.0: the era of revolutionary access.

Chris Macdonald

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Chris MacdonaldUniversity of Cambridge, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of modern healthcare is transitioning from a reactive, disease-centered paradigm (Medicine 2.0) toward a proactive, personalised model focused on maximising healthspan (Medicine 3.0). While this shift represents a vital optimisation of medical philosophy, it remains critically incomplete. This Perspective proposes a new paradigm (Medicine 4.0) which adds a foundational third dimension to the lifespan-healthspan model: radical access to both medical services and scientific ideas. The author analyses how commercial incentives, regulatory frameworks, and market forces frequently distort the production of scientific evidence, marginalise transformative, low-cost treatments, and delay paradigm shifts. Furthermore, the author examines the dual-edged nature of emerging digital health technologies, warning that monetisation through paywalls and engagement-driven ad models risks ossifying existing public health inequalities rather than democratising care. By realigning institutional incentives and dismantling structural obstructions to inquiry, Medicine 4.0 advocates for a return to the foundational Baconian principle that scientific knowledge must serve humanity. Ultimately, the author argues that medical progress must be evaluated not merely by its technological surface area, but by its total societal volume.

Indexed as

digital healthhealthcare accesshealthspanlifespanMedicine 3.0Medicine 4.0personalised medicinepreventive medicine

Identifiers

PMID42577141
PMCPMC13453668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.