Evidence map›Paper›PMID 42577027›Full record

ArticleKidney international reports2026

10-Year Trends in Heart Failure Among Patients With Dialysis and Nondialysis CKD.

Roosa Lankinen, Shunsuke Murata, Juan-Jesús Carrero, Karin Modig, Marie Evans, Anne-Laure Faucon

Abstract read
In one paragraph

Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roosa LankinenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Shunsuke MurataUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Juan-Jesús CarreroDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Karin ModigUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Marie EvansDepartment of Nephrology, Karolinska University Hospital, Stockholm, Sweden.
Anne-Laure FauconDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Funding

Medication Use and Adverse Events in CKDR01DK115534 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Alexander R Chang, Morgan Erika Grams · 2018 to 2026
$5.7M
NIDDK NIH HHS R01 DK115534
6 · The paper itself

Abstract

Introduction: This study explores the rates and temporal trends of heart failure (HF) in advanced chronic kidney disease (CKD) compared with the general population (GP). Methods: We included all patients with nondialysis dependent CKD stage G4 ( Results: Rates of HF-related hospitalization increased with more advanced stages of CKD, ranging from 3.7 to 6.8 times higher than those in the GP. Between 2011 and 2021, renin-angiotensin system inhibitor (RASi) and beta-blocker use remained stable and relatively low (44.5% to 70% for RASi), whereas diuretic prescription declined in nondialysis (ND)-CKD. This paralleled an important increase in the rates of HF-related hospitalization in CKD stage 4 (+51%), 5-ND (+36%), and HD (+30%), with a larger increase than that observed in the GP. In contrast, HF-related mortality steadily declined in both ND-CKD (up to -20.8% in CKD stage 4) and dialysis dependent CKD (up to -66% in HD), although slower than in the GP. Conclusion: Despite decline in HF-related mortality over the past decade-although slower than in the GP-HF-related hospitalization rates have risen substantially in advanced CKD, with a faster increase than those in the GP. These findings highlight the growing HF burden in CKD, and the need for targeted prevention and management strategies.

Indexed as

CKDdialysisdiureticsepidemiologyheart failuretemporal trends

Identifiers

PMID42577027
PMCPMC13453444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.