Evidence map›Paper›PMID 42577007›Full record

ArticleJTCVS techniques2026

Impact of ex vivo lung perfusion evaluation on donation after circulatory death in lung transplantation.

Mariana Gil-Barturen, Laura Donahoe, Marc de Perrot, Kazuhiro Yasufuku, Andrew Pierre, Elliot Wakeam, Thomas K Waddell, Shaf Keshavjee, Marcelo Cypel, Jonathan C Yeung

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Article in JTCVS techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mariana Gil-BarturenDepartment of Surgery, Miami Transplant Institute, University of Miami, Miami, Fla.
Laura DonahoeToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Marc de PerrotToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Kazuhiro YasufukuToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Andrew PierreToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Elliot WakeamToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Thomas K WaddellToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Shaf KeshavjeeToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Marcelo CypelToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Jonathan C YeungToronto Lung Transplant Program, Division of Thoracic Surgery, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: As the result of increased warm ischemia time and limited intraoperative evaluation, donation after circulatory death (DCD) donors might be considered greater risk, and use lags behind donation after brain death (DBD). Ex vivo lung perfusion (EVLP) provides an opportunity to better evaluate DCD lungs, and we sought to examine our outcomes. Methods: A single-center retrospective review of a prospectively collected database was performed for DCD donor lung transplants (LTx) from January 1, 2007, to August 8, 2024. DCD donors were stratified into EVLP (EVLP-DCD) and non-EVLP (non-EVLP-DCD) groups. Donor and recipient demographics, donor quality metrics, post-LTx outcomes, and overall survival were collected. Results: In total, 2282 LTx were performed from 2007 to 2024, and 467 (20.5%) were from DCD. EVLP was used in 257 (55%) of DCD. Between EVLP-DCD and non-EVLP-DCD, there was similar primary graft dysfunction grade 3 at 72 hours (14.0% vs 13.3%, Conclusions: Transplantation of DCD lungs evaluated by EVLP had comparable outcomes compared with non-EVLP-evaluated DCD lungs and DBD lungs. Liberal use of EVLP evaluation has led to safe and increased use of DCD lungs despite their unpredictably greater risk.

Indexed as

donation after circulatory deathex vivo lung perfusionlung transplant

Identifiers

PMID42577007
PMCPMC13453647

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.