ArticleThe journal of allergy and clinical immunology. Global2026
Ameliorative effects of
Article in The journal of allergy and clinical immunology. Global, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease marked by severe itching and eczematous lesions, primarily driven by immune system dysregulation. Current treatments largely focus on symptom relief rather than addressing underlying immune dysfunction. The parasitic nematode Objective: We sought to evaluate the therapeutic potential of Methods: Thirty-five mice were divided into 7 groups; all except from the normal control group were sensitized and challenged with 2,4-dinitrochlorobenzene to induce AD-like symptoms. Treatment groups received rCTL, topical or injected dexamethasone, or bacterial lysate. The prevention group was pretreated with rCTL (subcutaneously and intraperitoneally) before 2,4-dinitrochlorobenzene exposure. Dermatitis severity was assessed biweekly, and pruritus was quantified through blinded video analysis of scratching behavior. Serum IgE levels were measured via ELISA, and histopathologic analyses examined epidermal and dermal changes. Results: Conclusions:
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