Evidence map›Paper›PMID 42576958›Full record

ArticleGynecologic oncology reports2026

Pretreatment CT-defined sarcopenia is associated with worse survival in cervical cancer.

Leandro Santos de Araujo Resende, Miguel Soares Conceição, Rodrigo Menezes Jales, Patrick Nunes Pereira, Luis Otávio Sarian, Glauco Baiocchi, Sophie Derchain, Agnaldo Lopes da Silva Filho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leandro Santos de Araujo ResendeDepartment of Gynecology and Obstetrics, Botucatu Medical School, São Paulo State University, (UNESP), São Paulo, Brazil.
Miguel Soares ConceiçãoDepartment of Health Sciences, University of Sao Francisco, São Paulo, Brazil.
Rodrigo Menezes JalesDepartment of Obstetrics and Gynecology, School of Medical Science, State University of Campinas (UNICAMP), Campinas, Brazil.
Patrick Nunes PereiraDepartment of Obstetrics and Gynecology, School of Medical Science, State University of Campinas (UNICAMP), Campinas, Brazil.
Luis Otávio SarianDepartment of Obstetrics and Gynecology, School of Medical Science, State University of Campinas (UNICAMP), Campinas, Brazil.
Glauco BaiocchiDepartment of Gynecologic Oncology, AC Camargo Cancer Center, Sao Paulo, Brazil.
Sophie DerchainDepartment of Obstetrics and Gynecology, School of Medical Science, State University of Campinas (UNICAMP), Campinas, Brazil.
Agnaldo Lopes da Silva FilhoDepartment of Gynecology and Obstetrics, Botucatu Medical School, São Paulo State University, (UNESP), São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the prevalence and prognostic relevance of pretreatment computed tomography-defined sarcopenia in women with cervical cancer treated with definitive radiotherapy with or without concurrent chemotherapy. Methods: This retrospective cohort study included women aged 18 years or older with FIGO 2018 stage IB2 to IVA cervical cancer who initiated definitive radiotherapy, with or without radiosensitizing chemotherapy, between January 2016 and December 2018 at CAISM/UNICAMP, Campinas, Brazil. Follow-up continued through 2022 to ensure a minimum follow-up period to evaluate 5-year survival outcomes. Women with prior malignancy treated with chemotherapy or radiotherapy, unavailable or non-measurable pretreatment computed tomography, pregnancy, or death before treatment initiation were excluded. Pretreatment sarcopenia was defined as skeletal muscle index <38.9 cm Results: Among 210 included women, 79 (37.6%) had pretreatment sarcopenia. Most patients had squamous histology (176/210, 83.8%), advanced FIGO stage III/IV disease (120/210, 57.1%), and received chemotherapy (177/210, 84.3%). Sarcopenia was more frequent among women aged <50 years, premenopausal women, women with body mass index <25 kg/m Conclusion: Pretreatment CT-defined sarcopenia was common and associated with poorer survival outcomes in univariable analysis, although treatment response remained the strongest independent prognostic factor in women with cervical cancer treated with definitive chemoradiotherapy.

Indexed as

Cervical cancerCT scanSarcopenia

Identifiers

PMID42576958
PMCPMC13453474

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.