Evidence map›Paper›PMID 42576879›Full record

ArticleSustainable microbiology2025

Testing eukaryotic routes for heterologous production of ketocarotenoids in cyanobacteria.

Anika V Mahdi, Dennis N Wittmann, Sayali S Hanamghar, Oskar Zorć, Jialan Cao, G Alexander Groß, Poul Erik Jensen, David A Russo, Julie A Z Zedler

Abstract read
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In one paragraph

Article in Sustainable microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anika V MahdiSynthetic Biology of Photosynthetic Organisms, Matthias Schleiden Institute for Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743 Jena, Germany.
Dennis N WittmannSynthetic Biology of Photosynthetic Organisms, Matthias Schleiden Institute for Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743 Jena, Germany.
Sayali S HanamgharSynthetic Biology of Photosynthetic Organisms, Matthias Schleiden Institute for Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743 Jena, Germany.
Oskar ZorćSynthetic Biology of Photosynthetic Organisms, Matthias Schleiden Institute for Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743 Jena, Germany.
Jialan CaoDepartment of Physical Chemistry and Microreaction Technology, Institute of Chemistry and Bioengineering, Ilmenau University of Technology, 98693 Ilmenau, Germany.
G Alexander GroßDepartment of Physical Chemistry and Microreaction Technology, Institute of Chemistry and Bioengineering, Ilmenau University of Technology, 98693 Ilmenau, Germany.
Poul Erik JensenDepartment of Food Science, University of Copenhagen, 1958 Frederiksberg, Denmark.
David A RussoBioorganic Analytics, Institute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, 07743 Jena, Germany.
Julie A Z ZedlerSynthetic Biology of Photosynthetic Organisms, Matthias Schleiden Institute for Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743 Jena, Germany.ORCID https://orcid.org/0000-0002-0462-8810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigments and dyes are widely used in multiple industries. Ketocarotenoids are a highly sought-after group of pigments with a dark-red hue and strong antioxidant properties. Currently, chemical synthesis is the major route for ketocarotenoid production. However, the environmental risks and large demand have led to a call for the development of more sustainable sources. Cyanobacteria have promising properties for sustainable ketocarotenoid production: Some strains show fast growth, are genetically tractable, and natively produce ketocarotenoid precursors. Despite a few promising studies, engineering ketocarotenoid production in cyanobacteria is so far underexplored. Here, we expand the biosynthetic routes for ketocarotenoids by testing the astaxanthin synthase CrtS of

Indexed as

astaxanthinastaxanthin synthase CrtS, canthaxanthin, cyanobacteriaketocarotenoidsβ-carotene ketolase

Identifiers

PMID42576879
PMCPMC13375318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.