ArticleChemistryOpen2026
Efficient One-Pot Synthesis of Dibenzoxanthenes Using a Vinylimidazolium-Based Brønsted Acidic Ionic Liquid [VSBIM][Cl]: In Silico Evaluation of Drug-Likeness, ADMET Properties, PASS Analysis, Antiviral Activity Prediction, and Molecular Docking Studies.
Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Dibenzoxanthene derivatives have produced considerable interest due to their pharmacological, photophysical, and organic optoelectronic properties. Herein, a facile one-pot methodology was developed for the synthesis of 14-(aryl)-14H-dibenzo[a,j]xanthene derivatives employing 5 mol% of the Brønsted acidic ionic liquid 1-vinyl-3-(4-sulfobutyl) imidazolium chloride [VSBIM][Cl] as an efficient and recyclable catalyst under solvent-free conditions. This protocol enables the condensation of β-naphthol with varied aryl or heteroaryl aldehydes to afford dibenzoxanthenes under neat conditions at 110°C. Nineteen 14-(aryl)-14H-dibenzo[a,j]xanthene derivatives were prepared in good to high yields. The synthesized dibenzoxanthenes were characterized by
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