Evidence map›Paper›PMID 42576570›Full record

ArticleJournal of Parkinson's disease2026

A qPCR-based approach targeting the microbial gene marker

Yasuaki Mizutani, Tadashi Fujii, Yasuhiro Maeda, Kohei Funasaka, Eizaburo Ohno, Yoshiki Hirooka, Hirohisa Watanabe, Takumi Tochio

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yasuaki MizutaniDepartment of Neurology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.ORCID 0000-0002-5709-8526
Tadashi FujiiDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, Toyoake, Japan.
Yasuhiro MaedaOpen Facility Center, Fujita Health University, Toyoake, Aichi, Japan.
Kohei FunasakaDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, Toyoake, Japan.
Eizaburo OhnoDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, Toyoake, Japan.
Yoshiki HirookaDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, Toyoake, Japan.
Hirohisa WatanabeDepartment of Neurology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Takumi TochioDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, Toyoake, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundParkinson's disease (PD) is a multifactorial neurodegenerative disorder increasingly linked to gut microbiota alterations. However, despite advances in fecal microbiota profiling as a non-invasive approach to disease risk assessment, its clinical utility remains limited by a lack of functionally relevant microbial biomarkers.ObjectiveThis cross-sectional study aimed to identify a microbial gene marker reflecting metabolic potential associated with both the presence and severity of PD.MethodsFecal samples from patients with PD (

Indexed as

AkkermansiaAkkermansia nanA genemicrobiota alterationParkinson's diseasequantitative PCR

Identifiers

PMID42576570
PMCPMC13461883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.