Evidence map›Paper›PMID 42576311›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

Association between body mass index and unilateral hypoglossal nerve stimulation efficacy depends on the pattern of pharyngeal collapse in obstructive sleep apnea.

Daniel Vena, Eric J Kezirian, Andrew Wellman, David Kent, Mark D'Agostino, Joao L G C Monteiro, Ali Azarbarzin, Tom Chen, Scott A Sands, Phillip Huyett

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Daniel VenaDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Eric J KezirianDepartment of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California.
Andrew WellmanDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
David KentDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Mark D'AgostinoSouthern New England Ear, Nose and Throat Group, Middlesex Hospital, Middlesex, Connecticut.
Joao L G C MonteiroDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Ali AzarbarzinDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Tom ChenDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Phillip HuyettDepartment of Otolaryngology, Massachusetts Eye and Ear, Boston, MA.

Funding

Validation of a Phenotype Model to Predict Response to Alternative OSA TreatmentsR01HL102321 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2011 to 2025
$7.3M
Determination of the site of pharyngeal collapse in Obstructive Sleep Apnea patients from snoring soundsR01HL128658 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2016 to 2025
$4.3M
A Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4M
Upper airway collapsibility, loop gain and arousal threshold: an integrative therapeutic approach to obstructive sleep apneaR01HL160993 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KEZIRIAN, ERIC JAMES · 2022 to 2025
$2.6M
Recognizing and resolving laterally directed pharyngeal collapse for successful hypoglossal nerve stimulation therapy in OSAR01HL180582 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Vena · 2026 to 2026
$895k
NHLBI NIH HHS R01 HL102321NHLBI NIH HHS R01 HL128658NHLBI NIH HHS R01 HL146697NHLBI NIH HHS R01 HL160993NHLBI NIH HHS R01 HL180582
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug-induced Sleep EndoscopyObstructiveSite of pharyngeal collapseSleep Apnea

Identifiers

PMID42576311
PMCPMC13596096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.