Evidence map›Paper›PMID 42576198›Full record

ArticleBMC plant biology2026

Integrated transcriptomic and proteomic analyses provide insights into potential molecular mechanisms underlying globulin content variation in maize embryos.

Yan Cui, Meiyu E, Meijie Cao, Xin Lu, Yutong Zhang, Ruiqi Wang, Changhong Guo, Zhiqiang Zhou, Xinhai Li

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Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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9 authors.

Yan Cui *Key Laboratory of Molecular and Cytogenetics, College of Life Science and Technology, Harbin Normal University, Harbin, 150025, China.
Meiyu E *Key Laboratory of Molecular and Cytogenetics, College of Life Science and Technology, Harbin Normal University, Harbin, 150025, China.
Meijie CaoKey Laboratory of Molecular and Cytogenetics, College of Life Science and Technology, Harbin Normal University, Harbin, 150025, China.
Xin LuState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Yutong ZhangKey Laboratory of Molecular and Cytogenetics, College of Life Science and Technology, Harbin Normal University, Harbin, 150025, China.
Ruiqi WangState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Changhong GuoKey Laboratory of Molecular and Cytogenetics, College of Life Science and Technology, Harbin Normal University, Harbin, 150025, China. kaku3008@hrbnu.edu.cn.
Zhiqiang ZhouState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China. zhouzhiqiang@caas.cn.
Xinhai LiState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China. lixinhai@caas.cn.

Funding

Modern Agro-Industry Technology Research System of Maize CARS-02-02National Natural Science Foundation of China 32572311
6 · The paper itself

Abstract

backgroundGlobulin in maize kernels is a high-quality protein, which is mainly enriched in the embryo. However, academic research focusing on the molecular mechanism underlying globulin synthesis remains relatively limited to date. Therefore, unveiling the molecular mechanism of globulin synthesis in maize embryos is of great significance for the breeding of high-protein maize varieties. To gain better insights into this mechanism, we integrated transcriptomic and proteomic analysis to identify differentially expressed genes (DEGs) and differentially expressed proteins (DEPs) between two types of materials with distinct globulin contents.

resultsTwo maize inbred lines were selected for this study, including B73 (low globulin content) and HP434 (high globulin content). Integrated transcriptomic and proteomic analyses revealed that DEGs and DEPs were predominantly enriched in the endoplasmic reticulum (ER) protein processing pathway. Significantly, most of these DEGs and DEPs belonged to the heat shock protein (HSP) family. This indicates that globulin synthesis is closely related to the genes of this family, especially the small molecule heat shock proteins.

conclusionsThe high expression of HSP family genes in HP434 might alleviate the increased ER processing pressure caused by the aggregation of misfolded proteins during the high-abundance synthesis of globulin, thereby contributing to the synthesis of globulin in the ER.

Indexed as

GlobulinsPlant ProteinsSeedsTranscriptomeZea maysGene Expression ProfilingGene Expression Regulation, PlantHeat-Shock ProteinsProteomeProteomicsGlobulinsHeat-Shock ProteinsPlant ProteinsProteomeGlobulinMaizeProtein processingProteomeTranscriptome

Identifiers

PMID42576198
PMCPMC13455331

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