ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026
Multidimensional workplace stressors differentially impact cognitive trajectories.
Monica E Walters, Kiana A Scambray, Jordan D Palms, Robrielle M Pierce, Ketlyne Sol, Laura B Zahodne
Abstract read
In one paragraphArticle in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
6 authors.
Kiana A ScambrayDepartment of Psychology, University of Michigan, Ann Arbor, Michigan, USA.
Jordan D PalmsDepartment of Psychology, University of Michigan, Ann Arbor, Michigan, USA.
Robrielle M PierceDepartment of Psychology, University of Michigan, Ann Arbor, Michigan, USA.
Ketlyne SolComprehensive Center for Brain Health, Department of Neurology, Miller School of Medicine, University of Miami, Boca Raton, Florida, USA.
Laura B ZahodneDepartment of Psychology, University of Michigan, Ann Arbor, Michigan, USA.
Funding
Michigan Institute for Clinical and Health Research (MICHR)UM1TR004404 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Julie C Lumeng · 2023 to 2026
$39.8MResearch Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2MStatistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2MMichigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1MPilot CoreP30AG066582 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Julie PW Bynum · 2020 to 2026
$7.2MMechanisms of inequalities in ADRD risk across race and place in the Michigan Cognitive Aging ProjectR01AG082307 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Laura B Zahodne · 2023 to 2026
$3.8MRisk and resilience mechanisms underlying race disparities in ADRD: An examination of neighborhood resources, social networks, brain integrity, and cognitionK01AG073588 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOL, KETLYNE · 2021 to 2025
$637kNCATS NIH HHS UM1 TR004404NIA NIH HHS K01 AG073588NIA NIH HHS K01AG073588NIA NIH HHS P30 AG012846NIA NIH HHS P30AG012846NIA NIH HHS P30 AG024824NIA NIH HHS P30AG024824NIA NIH HHS P30 AG053760NIA NIH HHS P30AG053760NIA NIH HHS P30 AG066582NIA NIH HHS P30AG066582NIA NIH HHS R01 AG082307NIA NIH HHS R01AG082307NIH HHS CTSAUM1TR004404
6 · The paper itselfAbstract
introductionLittle research has assessed detailed occupational exposures in relation to the dementia exposome. We characterized patterns of multidimensional workplace stressors in relation to cognitive trajectories and racial disparities.
methodsWe included 704 participants from the Michigan Cognitive Aging Project (M
resultsFive profiles emerged. Black participants were more likely to show higher-stress profiles; this difference was explained by education. The profile with low job control/limited other stressors had the lowest initial cognition, especially among Black participants. The profile with high emotional labor/job demands had the fastest cognitive decline. DISCUSSION: Workplace stress is a relevant, under-recognized aspect of the dementia exposome.
Indexed as
CognitionCognitive AgingCognitive DysfunctionOccupational StressStress, PsychologicalWorkplaceAgedBlack or African AmericanFemaleHumansMaleMichiganMiddle AgedNeuropsychological TestsSocioeconomic Disparities in HealthWorking Conditionsattentioncognitive agingepisodic memoryexposomeheterogeneityoccupational exposuresO*NETracial disparitiessocioeconomic statusstressorsverbal fluencyworking memory
Identifiers
PMID42576161
PMCPMC13457349
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