Evidence map›Paper›PMID 42576154›Full record

Trial reportDrug and alcohol review2026

Assessing the Concurrent Validity of the Australian Treatment Outcomes Profile in a Methamphetamine Dependent Treatment-Seeking Population.

Brendan Clifford, Rachel M Deacon, Kristie Mammen, Krista J Siefried, Nadine Ezard, Nicholas Lintzeris

Abstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Drug and alcohol review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brendan CliffordAlcohol and Drug Service, St Vincent's Hospital Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0002-9178-9013
Rachel M DeaconNew South Wales Drug and Alcohol Clinical Research and Improvement Network (DACRIN), Sydney, Australia.
Kristie MammenNew South Wales Drug and Alcohol Clinical Research and Improvement Network (DACRIN), Sydney, Australia.
Krista J SiefriedAlcohol and Drug Service, St Vincent's Hospital Sydney, Sydney, Australia.
Nadine EzardAlcohol and Drug Service, St Vincent's Hospital Sydney, Sydney, Australia.
Nicholas LintzerisNew South Wales Drug and Alcohol Clinical Research and Improvement Network (DACRIN), Sydney, Australia.

Funding

National Health and Medical Research Council APP1109466St Vincent's Inclusive Health ProgramThe Curran Foundation
6 · The paper itself

Abstract

introductionThe Australian Treatment Outcomes Profile (ATOP) is a brief clinical tool assessing substance use, health and well-being used in Australian alcohol and other drug treatment services. It is validated for use with clients using alcohol, opioids and cannabis, but not yet for clients who primarily use methamphetamine.

methodsAn embedded validation study was undertaken in treatment-seeking adults enrolled in a randomised double-blind placebo-controlled trial of lisdexamfetamine for methamphetamine dependence with sites in New South Wales, South Australia and Victoria. Participant demographics were collected during study screening. The ATOP and comparators (Time Line Follow Back, Opiate Treatment Index, Depression Anxiety Stress Scale, WHOQOL-BREF and Personal Wellbeing Index) were collected at baseline. Continuous ATOP items were analysed using Pearson's correlation coefficient, and dichotomous items were analysed using Fleiss's κ. Agreement was rated as strong where measures were ≥ 0.50, moderate where agreement was 0.30-0.49, and weak where < 0.30.

resultsOne hundred and eighteen study participants (2018-2020) had data for concurrent validity analysis. Strong validity was demonstrated for physical health, psychological health, quality of life, injecting drug use and crime items, and for days of use for amphetamines, alcohol, cannabis and cocaine. There was weak validity for days of use for benzodiazepines. Heroin use days and other opioid use days were endorsed by fewer than five participants and were therefore unable to be assessed. DISCUSSION AND

conclusionsThe ATOP is valid for use in a treatment-seeking methamphetamine-dependent population, expanding the range of tools for assessment and standardised outcome monitoring across different settings and services.

Indexed as

Amphetamine-Related DisordersMethamphetamineAdultAustraliaDouble-Blind MethodFemaleHumansMaleMiddle AgedQuality of LifeReproducibility of ResultsTreatment OutcomeMethamphetamineamphetamine‐related disordersmethamphetamineoutcome assessmentpatient reported outcome measuressubstance use

Identifiers

PMID42576154
PMCPMC13457504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.